Sequence Detail

ID/Version

Q61169 Q9QZK3 P97729 Q3UQJ2 (UniProt | EBI)

Last sequence update: 2008-11-25
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Transcription factor GATA-6;AltName: Full=GATA-binding factor 6;

Provider

SWISS-PROT

Sequence

Polypeptide 589 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gata6	GATA binding protein 6	132	197	3	24

Sequence references in MGI

J:34197 Morrisey EE, et al., GATA-6: a zinc finger transcription factor that is expressed in multiple cell lineages derived from lateral mesoderm. Dev Biol. 1996 Jul 10;177(1):309-22
J:35294 Narita N, et al., The gene for transcription factor GATA-6 resides on mouse chromosome 18 and is expressed in myocardium and vascular smooth muscle. Genomics. 1996 Sep 1;36(2):345-8
J:59167 Brewer A, et al., The human and mouse GATA-6 genes utilize two promoters and two initiation codons. J Biol Chem. 1999 Dec 31;274(53):38004-16
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101354 Rath N, et al., LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding. Mol Cell Biol. 2005 Oct;25(20):8864-73
J:151961 Kodo K, et al., GATA6 mutations cause human cardiac outflow tract defects by disrupting semaphorin-plexin signaling. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):13933-8
J:326594 Lee KH, et al., SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer. Development. 2004 Oct;131(19):4709-23