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Sequence Detail
ID/Version
Q61220 Q80UM5 (UniProt | EBI) Last sequence update: 2013-09-18
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Protein kinase C-binding protein NELL2;AltName: Full=MEL91 protein;AltName: Full=NEL-like protein 2;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 819 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Nell2 NEL-like 2 26 114 4 14
Sequence references in MGI J:227045 Jaworski A, et al., Operational redundancy in axon guidance through the multifunctional receptor Robo3 and its ligand NELL2. Science. 2015 Nov 20;350(6263):961-5
J:286386 Pak JS, et al., NELL2-Robo3 complex structure reveals mechanisms of receptor activation for axon guidance. Nat Commun. 2020 Mar 20;11(1):1489
J:290452 Kiyozumi D, et al., NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science. 2020 Jun 5;368(6495):1132-1135
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:335479 Kiyozumi D, et al., A small secreted protein NICOL regulates lumicrine-mediated sperm maturation and male fertility. Nat Commun. 2023 Apr 24;14(1):2354

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory