Sequence Detail

ID/Version

Q61234 Q8VEF3 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Alpha-1-syntrophin;AltName: Full=59 kDa dystrophin-associated protein A1 acidic component 1;AltName: Full=Syntrophin-1;

Provider

SWISS-PROT

Sequence

Polypeptide 503 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Snta1	syntrophin, acidic 1	47	97	3	19

Sequence references in MGI

J:20636 Adams ME, et al., Two forms of mouse syntrophin, a 58 kd dystrophin-associated protein, differ in primary structure and tissue distribution. Neuron. 1993 Sep;11(3):531-40
J:28976 Madhavan R, et al., Interactions between dystrophin glycoprotein complex proteins. Biochemistry. 1995 Sep 26;34(38):12204-9
J:31846 Brenman JE, et al., Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and alpha1-syntrophin mediated by PDZ domains. Cell. 1996 Mar 8;84(5):757-67
J:38353 Newbell BJ, et al., Ca2+-calmodulin binding to mouse alpha1 syntrophin: syntrophin is also a Ca2+-binding protein. Biochemistry. 1997 Feb 11;36(6):1295-305
J:41623 Peters MF, et al., Differential association of syntrophin pairs with the dystrophin complex. J Cell Biol. 1997 Jul 14;138(1):81-93
J:54511 Chockalingam PS, et al., Pleckstrin homology domain 1 of mouse alpha 1-syntrophin binds phosphatidylinositol 4,5-bisphosphate. Biochemistry. 1999 Apr 27;38(17):5596-602
J:119852 Loh NY, et al., Assembly of multiple dystrobrevin-containing complexes in the kidney. J Cell Sci. 2000 Aug;113(Pt 15):2715-24
J:184367 Joe MK, et al., Myocilin interacts with syntrophins and is member of dystrophin-associated protein complex. J Biol Chem. 2012 Apr 13;287(16):13216-27
J:213907 Oak SA, et al., Mouse alpha1-syntrophin binding to Grb2: further evidence of a role for syntrophin in cell signaling. Biochemistry. 2001 Sep 18;40(37):11270-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89