Sequence Detail

ID/Version

Q61239 Q921F7 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha; EC=2.5.1.58 {ECO:0000250|UniProtKB:P49354}; EC=2.5.1.59 {ECO:0000305|PubMed:14622576};AltName: Full=CAAX farnesyltransferase subunit alpha;AltName: F

Provider

SWISS-PROT

Sequence

Polypeptide 377 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fnta	farnesyltransferase, CAAX box, alpha	53	99	3	8

Sequence references in MGI

J:29641 Shirasawa H, et al., Cloning and sequencing of the murine farnesyltransferase alpha-encoding cDNA from a cell line which expresses the human papillomavirus type-16 E6 gene. Gene. 1995 Oct 27;164(2):373-4
J:86639 Luo ZG, et al., Implication of geranylgeranyltransferase I in synapse formation. Neuron. 2003 Nov 13;40(4):703-17
J:123768 Coffinier C, et al., From the Cover: HIV protease inhibitors block the zinc metalloproteinase ZMPSTE24 and lead to an accumulation of prelamin A in cells. Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13432-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89