Sequence Detail

ID/Version

Q61362 D3Z2P2 Q4FJW9 Q8BKL8 B0FEU7 Q3U291 Q99J84 (UniProt | EBI)

Last sequence update: 2014-05-14
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Chitinase-3-like protein 1;AltName: Full=BRP39 protein;AltName: Full=Breast regression protein 39;AltName: Full=Cartilage glycoprotein 39; Short=CGP-39; Short=GP-39;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 389 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Chi3l1	chitinase 3 like 1	31	101	2	13

Sequence references in MGI

J:21836 Morrison BW, et al., neu and ras initiate murine mammary tumors that share genetic markers generally absent in c-myc and int-2-initiated tumors. Oncogene. 1994 Dec;9(12):3417-26
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:124923 Mizoguchi E, Chitinase 3-like-1 exacerbates intestinal inflammation by enhancing bacterial adhesion and invasion in colonic epithelial cells. Gastroenterology. 2006 Feb;130(2):398-411
J:148490 Lee CG, et al., Role of breast regression protein 39 (BRP-39)/chitinase 3-like-1 in Th2 and IL-13-induced tissue responses and apoptosis. J Exp Med. 2009 May 11;206(5):1149-66
J:180536 Chen CC, et al., Carbohydrate-binding motif in chitinase 3-like 1 (CHI3L1/YKL-40) specifically activates Akt signaling pathway in colonic epithelial cells. Clin Immunol. 2011 Sep;140(3):268-75
J:244035 Dela Cruz CS, et al., Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung antibacterial responses. Cell Host Microbe. 2012 Jul 19;12(1):34-46
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89