Sequence Detail

ID/Version

Q61391 Q8K251 Q6NXX5 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Neprilysin; EC=3.4.24.11 {ECO:0000250|UniProtKB:P08473};AltName: Full=Atriopeptidase;AltName: Full=Enkephalinase;AltName: Full=Neutral endopeptidase 24.11 {ECO:0000303|PubMed:1374101}; Short=NEP; Short=Neutral endopep

Provider

SWISS-PROT

Sequence

Polypeptide 750 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mme	membrane metallo endopeptidase	92	108	2	22

Sequence references in MGI

J:761 Chen CY, et al., Murine common acute lymphoblastic leukemia antigen (CD10 neutral endopeptidase 24.11). Molecular characterization, chromosomal localization, and modeling of the active site. J Immunol. 1992 May 1;148(9):2817-25
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:244998 Auer-Grumbach M, et al., Rare Variants in MME, Encoding Metalloprotease Neprilysin, Are Linked to Late-Onset Autosomal-Dominant Axonal Polyneuropathies. Am J Hum Genet. 2016 Sep 01;99(3):607-623
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89