Sequence Detail

ID/Version

Q61490 Q8CDA5 Q8R2T0 O70136 (UniProt | EBI)

Last sequence update: 2004-05-24
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=CD166 antigen;AltName: Full=Activated leukocyte cell adhesion molecule {ECO:0000303|PubMed:9209500};AltName: Full=BEN {ECO:0000303|PubMed:15345243};AltName: Full=Protein DM-GRASP {ECO:0000303|PubMed:8089660};AltName: CD_antigen=CD166;Flags:

Provider

SWISS-PROT

Sequence

Polypeptide 583 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Alcam	activated leukocyte cell adhesion molecule	25	128	4	7

Sequence references in MGI

J:19352 Kanki JP, et al., The molecular cloning and characterization of potential chick DM-GRASP homologs in zebrafish and mouse. J Neurobiol. 1994 Jul;25(7):831-45
J:40942 Bowen MA, et al., Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding. Eur J Immunol. 1997 Jun;27(6):1469-78
J:93205 Weiner JA, et al., Axon fasciculation defects and retinal dysplasias in mice lacking the immunoglobulin superfamily adhesion molecule BEN/ALCAM/SC1. Mol Cell Neurosci. 2004 Sep;27(1):59-69
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:196986 Iolyeva M, et al., Novel role for ALCAM in lymphatic network formation and function. FASEB J. 2013 Mar;27(3):978-90
J:213747 Chitteti BR, et al., CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche. Blood. 2014 Jul 24;124(4):519-29
J:245885 Hooker RA, et al., Activated leukocyte cell adhesion molecule (ALCAM or CD166) modulates bone phenotype and hematopoiesis. J Musculoskelet Neuronal Interact. 2015 Mar;15(1):83-94
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89