Sequence Detail

ID/Version

Q61553 Q05DK3 Q7TN32 Q80V75 O09099 O09156 (UniProt | EBI)

Last sequence update: 2007-05-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Fascin;AltName: Full=Singed-like protein;

Provider

SWISS-PROT

Sequence

Polypeptide 493 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fscn1	fascin actin-bundling protein 1	85	108	4	16

Sequence references in MGI

J:25101 Edwards RA, et al., Cloning and expression of a murine fascin homolog from mouse brain. J Biol Chem. 1995 May 5;270(18):10764-70
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:168387 Chen L, et al., Migrastatin analogues target fascin to block tumour metastasis. Nature. 2010 Apr 15;464(7291):1062-6
J:196252 Li X, et al., Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton. Oncogene. 2012 Feb 2;31(5):595-610
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:214682 Wei Z, et al., Rufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axons. J Neurochem. 2014 Sep;130(5):678-92
J:260288 Deinhardt K, et al., Neuronal growth cone retraction relies on proneurotrophin receptor signaling through Rac. Sci Signal. 2011 Dec 6;4(202):ra82
J:276418 Jansen S, et al., Mechanism of actin filament bundling by fascin. J Biol Chem. 2011 Aug 26;286(34):30087-96
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89