Sequence Detail

ID/Version

Q61555 E9QJZ4 Q63957 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Fibrillin-2 {ECO:0000303|PubMed:32329225};Contains: RecName: Full=Placensin {ECO:0000303|PubMed:32329225};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 2907 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fbn2	fibrillin 2	28	119	4	17

Sequence references in MGI

J:16152 Li X, et al., Fibrillin genes map to regions of conserved mouse/human synteny on mouse chromosomes 2 and 18. Genomics. 1993 Dec;18(3):667-72
J:25216 Zhang H, et al., Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils. J Cell Biol. 1995 May;129(4):1165-76
J:70592 Arteaga-Solis E, et al., Regulation of limb patterning by extracellular microfibrils. J Cell Biol. 2001 Jul 23;154(2):275-81
J:110586 Carta L, et al., Fibrillins 1 and 2 perform partially overlapping functions during aortic development. J Biol Chem. 2006 Mar 24;281(12):8016-23
J:165256 Nistala H, et al., Fibrillin-1 and -2 differentially modulate endogenous TGF-beta and BMP bioavailability during bone formation. J Cell Biol. 2010 Sep 20;190(6):1107-21
J:235251 Tiedemann K, et al., Fibrillin-1 directly regulates osteoclast formation and function by a dual mechanism. J Cell Sci. 2013 Sep 15;126(Pt 18):4187-94
J:313847 Yu Y, et al., Placensin is a glucogenic hormone secreted by human placenta. EMBO Rep. 2020 Jun 4;21(6):e49530