Sequence Detail

ID/Version

Q61581 O88812 Q9EQW0 (UniProt | EBI)

Last sequence update: 2002-09-19
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Insulin-like growth factor-binding protein 7; Short=IBP-7; Short=IGF-binding protein 7; Short=IGFBP-7;AltName: Full=MAC25 protein;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 281 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Igfbp7	insulin-like growth factor binding protein 7	13	115	3	19

Sequence references in MGI

J:36297 Kato MV, et al., A follistatin-like gene, mac25, may act as a growth suppressor of osteosarcoma cells. Oncogene. 1996 Mar 21;12(6):1361-4
J:59383 Komatsu S, et al., Methylation and downregulated expression of mac25/insulin-like growth factor binding protein-7 is associated with liver tumorigenesis in SV40T/t antigen transgenic mice, screened by restriction landmark genomic scanning for methylation (RLGS-M). Biochem Biophys Res Commun. 2000 Jan 7;267(1):109-17
J:71965 Kanemitsu N, et al., Characterization of the promoter of the murine mac25 gene. Biochem Biophys Res Commun. 2000 Dec 9;279(1):251-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89