Sequence Detail

ID/Version

Q61644 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Protein kinase C and casein kinase substrate in neurons protein 1;AltName: Full=Syndapin-1;

Provider

SWISS-PROT

Sequence

Polypeptide 441 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pacsin1	protein kinase C and casein kinase substrate in neurons 1	52	103	4	18

Sequence references in MGI

J:55204 Plomann M, et al., PACSIN, a brain protein that is upregulated upon differentiation into neuronal cells. Eur J Biochem. 1998 Aug 15;256(1):201-11
J:66805 Modregger J, et al., All three PACSIN isoforms bind to endocytic proteins and inhibit endocytosis. J Cell Sci. 2000 Dec;113 Pt 24:4511-21
J:101755 Braun A, et al., EHD proteins associate with syndapin I and II and such interactions play a crucial role in endosomal recycling. Mol Biol Cell. 2005 Aug;16(8):3642-58
J:114364 Cuajungco MP, et al., PACSINs bind to the TRPV4 cation channel. PACSIN 3 modulates the subcellular localization of TRPV4. J Biol Chem. 2006 Jul 7;281(27):18753-62
J:160320 Rao Y, et al., Molecular basis for SH3 domain regulation of F-BAR-mediated membrane deformation. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8213-8
J:180017 Koch D, et al., Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I. EMBO J. 2011 Dec 14;30(24):4955-69
J:201934 Liu Y, et al., PACSIN1, a Tau-interacting protein, regulates axonal elongation and branching by facilitating microtubule instability. J Biol Chem. 2012 Nov 16;287(47):39911-24
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89