Sequence Detail

ID/Version

Q61781 A2A4G4 Q91VQ4 Q99LE0 (UniProt | EBI)

Last sequence update: 2003-07-25
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Keratin, type I cytoskeletal 14;AltName: Full=Cytokeratin-14; Short=CK-14;AltName: Full=Keratin-14; Short=K14;

Provider

SWISS-PROT

Sequence

Polypeptide 484 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Krt14	keratin 14	34	214	12	25

Sequence references in MGI

J:30054 Knapp B, et al., Three cDNA sequences of mouse type I keratins. Cellular localization of the mRNAs in normal and hyperproliferative tissues. J Biol Chem. 1987 Jan 15;262(2):938-45
J:76311 Peters B, et al., Complete cytolysis and neonatal lethality in keratin 5 knockout mice reveal its fundamental role in skin integrity and in epidermolysis bullosa simplex. Mol Biol Cell. 2001 Jun;12(6):1775-89
J:83640 Ravindranath RM, et al., Amelogenin interacts with cytokeratin-5 in ameloblasts during enamel growth. J Biol Chem. 2003 May 30;278(22):20293-302
J:108710 Tong X, et al., Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. Genes Dev. 2006 May 15;20(10):1353-64
J:138481 Spazierer D, et al., Stress-induced recruitment of epiplakin to keratin networks increases their resistance to hyperphosphorylation-induced disruption. J Cell Sci. 2008 Mar 15;121(Pt 6):825-33
J:229462 Allen EH, et al., Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy. Hum Mol Genet. 2016 Mar 15;25(6):1176-91
J:233599 Rietscher K, et al., Growth Retardation, Loss of Desmosomal Adhesion, and Impaired Tight Junction Function Identify a Unique Role of Plakophilin 1 In Vivo. J Invest Dermatol. 2016 Jul;136(7):1471-8
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:322687 Bouameur JE, et al., Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure. J Invest Dermatol. 2014 Nov;134(11):2776-2783
J:322809 Roth W, et al., Cytokines as genetic modifiers in K5-/- mice and in human epidermolysis bullosa simplex. Hum Mutat. 2009 May;30(5):832-41