Sequence Detail

ID/Version

Q61824 F8VQN4 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Disintegrin and metalloproteinase domain-containing protein 12; Short=ADAM 12; EC=3.4.24.-;AltName: Full=Meltrin-alpha;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 903 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Adam12	ADAM metallopeptidase domain 12	13	102	3	4

Sequence references in MGI

J:30529 Yagami-Hiromasa T, et al., A metalloprotease-disintegrin participating in myoblast fusion [see comments]. Nature. 1995 Oct 19;377(6550):652-6
J:48131 Kurisaki T, et al., Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo. Mech Dev. 1998 May;73(2):211-5
J:113894 Galliano MF, et al., Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion. J Biol Chem. 2000 May 5;275(18):13933-9
J:243545 Suzuki A, et al., Meltrin alpha cytoplasmic domain interacts with SH3 domains of Src and Grb2 and is phosphorylated by v-Src. Oncogene. 2000 Nov 30;19(51):5842-50