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Sequence Detail
ID/Version
Q61831 Q9R0U6 (UniProt | EBI) Last sequence update: 1997-11-01
Last annotation update: 2024-11-27
Sequence
description
from provider
RecName: Full=Mitogen-activated protein kinase 10; Short=MAP kinase 10; Short=MAPK 10; EC=2.7.11.24;AltName: Full=MAP kinase p49 3F12;AltName: Full=Stress-activated protein kinase JNK3;AltName: Full=c-Jun N-terminal kinase 3;
Provider SWISS-PROT
Sequence
Polypeptide 464 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Mapk10 mitogen-activated protein kinase 10 35 114 3 14
Sequence references in MGI J:31286 Martin JH, et al., Developmental expression in the mouse nervous system of the p493F12 SAP kinase. Brain Res Mol Brain Res. 1996 Jan;35(1-2):47-57
J:43658 Yang DD, et al., Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene. Nature. 1997 Oct 23;389(6653):865-70
J:57455 Koyano S, et al., A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1. FEBS Lett. 1999 Sep 3;457(3):385-8
J:64817 Ito M, et al., JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a Scaffold factor in the JNK signaling pathway. Mol Cell Biol. 1999 Nov;19(11):7539-48
J:126083 Kim Y, et al., MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival. J Exp Med. 2007 Sep 3;204(9):2063-74
J:186089 Yoshitane H, et al., JNK regulates the photic response of the mammalian circadian clock. EMBO Rep. 2012 May;13(5):455-61
J:220433 Atkinson PJ, et al., Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons. Hear Res. 2011 Aug;278(1-2):77-85
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory