Sequence Detail

ID/Version

Q61851 Q61564 Q63834 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Fibroblast growth factor receptor 3; Short=FGFR-3; EC=2.7.10.1;AltName: Full=Heparin-binding growth factor receptor;AltName: CD_antigen=CD333;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 801 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fgfr3	fibroblast growth factor receptor 3	172	190	3	43

Sequence references in MGI

J:4088 Katoh O, et al., Isolation of the complementary DNA encoding a mouse heparin-binding growth factor receptor with the use of a unique kinase insert sequence. Cancer Res. 1993 Mar 1;53(5):1136-41
J:19402 Ornitz DM, et al., Ligand specificity and heparin dependence of fibroblast growth factor receptors 1 and 3. J Biol Chem. 1992 Aug 15;267(23):16305-11
J:30011 Chellaiah AT, et al., Fibroblast growth factor receptor (FGFR) 3. Alternative splicing in immunoglobulin-like domain III creates a receptor highly specific for acidic FGF/FGF-1. J Biol Chem. 1994 Apr 15;269(15):11620-7
J:32105 Deng C, et al., Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell. 1996 Mar 22;84(6):911-21
J:32991 Colvin JS, et al., Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3. Nat Genet. 1996 Apr;12(4):390-7
J:50677 Weinstein M, et al., FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung. Development. 1998 Sep;125(18):3615-23
J:88289 Cho JY, et al., Defective lysosomal targeting of activated fibroblast growth factor receptor 3 in achondroplasia. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):609-14
J:175280 Gattineni J, et al., Regulation of serum 1,25(OH)2Vitamin D3 levels by fibroblast growth factor 23 is mediated by FGF receptors 3 and 4. Am J Physiol Renal Physiol. 2011 Aug;301(2):F371-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89