Sequence Detail

ID/Version

Q61884 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Meiosis-specific nuclear structural protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 491 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mns1	meiosis-specific nuclear structural protein 1	23	99	3	5

Sequence references in MGI

J:19855 Furukawa K, et al., cDNA cloning and functional characterization of a meiosis-specific protein (MNS1) with apparent nuclear association. Chromosome Res. 1994 Mar;2(2):99-113
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:183398 Zhou J, et al., MNS1 is essential for spermiogenesis and motile ciliary functions in mice. PLoS Genet. 2012 Mar;8(3):e1002516
J:265340 Ta-Shma A, et al., Homozygous loss-of-function mutations in MNS1 cause laterality defects and likely male infertility. PLoS Genet. 2018 Aug;14(8):e1007602
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:338030 Zhou L, et al., Structures of sperm flagellar doublet microtubules expand the genetic spectrum of male infertility. Cell. 2023 Jun 22;186(13):2897-2910.e19
J:342625 Chen Z, et al., De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking. Cell. 2023 Nov 9;186(23):5041-5053.e19
J:343412 Cao H, et al., BBOF1 is required for sperm motility and male fertility by stabilizing the flagellar axoneme in mice. Cell Mol Life Sci. 2023 May 17;80(6):152
J:352387 Tai L, et al., In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov. 2023 Nov 21;9(1):116