Sequence Detail

ID/Version

Q62083 E9PY04 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=PRKCA-binding protein;AltName: Full=Protein interacting with C kinase 1;AltName: Full=Protein kinase C-alpha-binding protein;

Provider

SWISS-PROT

Sequence

Polypeptide 416 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pick1	protein interacting with C kinase 1	95	102	3	7

Sequence references in MGI

J:41185 Staudinger J, et al., PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J Cell Biol. 1995 Feb;128(3):263-71
J:51893 Torres R, et al., PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands. Neuron. 1998 Dec;21(6):1453-63
J:113830 Staudinger J, et al., Specific interaction of the PDZ domain protein PICK1 with the COOH terminus of protein kinase C-alpha. J Biol Chem. 1997 Dec 19;272(51):32019-24
J:113845 Dev KK, et al., The protein kinase C alpha binding protein PICK1 interacts with short but not long form alternative splice variants of AMPA receptor subunits. Neuropharmacology. 1999 May;38(5):635-44
J:114768 Perroy J, et al., PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7. EMBO J. 2002 Jun 17;21(12):2990-9
J:165060 Clem RL, et al., PICK1 regulates incorporation of calcium-permeable AMPA receptors during cortical synaptic strengthening. J Neurosci. 2010 May 5;30(18):6360-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89