Sequence Detail

ID/Version

Q62165 Q61141 Q61094 Q61497 (UniProt | EBI)

Last sequence update: 2001-07-11
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Dystroglycan 1 {ECO:0000312|MGI:MGI:101864};AltName: Full=Dystroglycan {ECO:0000303|PubMed:9175728};AltName: Full=Dystrophin-associated glycoprotein 1 {ECO:0000312|MGI:MGI:101864};Contains: RecName: Full=Alpha-dystroglycan; Short=

Provider

SWISS-PROT

Sequence

Polypeptide 893 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dag1	dystroglycan 1	144	148	3	84

Sequence references in MGI

J:20705 Gorecki DC, et al., Dystroglycan: brain localisation and chromosome mapping in the mouse. Hum Mol Genet. 1994 Sep;3(9):1589-97
J:30104 Brancaccio A, et al., Cloning and sequencing of mouse skeletal muscle alpha-dystroglycan. Matrix Biol. 1995 Oct;14(8):681-5
J:35239 Yotsumoto S, et al., Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage. Hum Mol Genet. 1996 Sep;5(9):1259-67
J:40601 Williamson RA, et al., Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null mice. Hum Mol Genet. 1997 Jun;6(6):831-41
J:77280 Sherman DL, et al., Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy. Neuron. 2001 Jun;30(3):677-87
J:82929 Henion TR, et al., Expression of dystroglycan, fukutin and POMGnT1 during mouse cerebellar development. Brain Res Mol Brain Res. 2003 Apr 10;112(1-2):177-81
J:83782 Saito F, et al., Unique role of dystroglycan in peripheral nerve myelination, nodal structure, and sodium channel stabilization. Neuron. 2003 Jun 5;38(5):747-58
J:84372 Previtali SC, et al., Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles. J Neurosci. 2003 Jul 2;23(13):5520-30
J:93985 Bozic D, et al., The structure of the N-terminal region of murine skeletal muscle alpha-dystroglycan discloses a modular architecture. J Biol Chem. 2004 Oct 22;279(43):44812-6
J:150222 Ayalon G, et al., An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan. Cell. 2008 Dec 26;135(7):1189-200
J:155796 Yoshida-Moriguchi T, et al., O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding. Science. 2010 Jan 1;327(5961):88-92
J:200440 McDearmon EL, et al., Brain alpha-dystroglycan displays unique glycoepitopes and preferential binding to laminin-10/11. FEBS Lett. 2006 Jun 12;580(14):3381-5
J:223355 Suh J, et al., FE65 and FE65L1 amyloid precursor protein-binding protein compound null mice display adult-onset cataract and muscle weakness. FASEB J. 2015 Jun;29(6):2628-39
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89