Sequence Detail

ID/Version

Q62191 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase TRIM21; EC=2.3.2.27 {ECO:0000269|PubMed:17579016};AltName: Full=52 kDa Ro protein;AltName: Full=52 kDa ribonucleoprotein autoantigen Ro/SS-A;AltName: Full=Ro(SS-A);AltName: Full=Sjoegren syndrome type A an

Provider

SWISS-PROT

Sequence

Polypeptide 470 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trim21	tripartite motif-containing 21	69	101	6	12

Sequence references in MGI

J:32812 Keech CL, et al., Structural differences between the human and mouse 52-kD Ro autoantigens associated with poorly conserved autoantibody activity across species. Clin Exp Immunol. 1996 May;104(2):255-63
J:149427 Kong HJ, et al., Cutting edge: autoantigen Ro52 is an interferon inducible E3 ligase that ubiquitinates IRF-8 and enhances cytokine expression in macrophages. J Immunol. 2007 Jul 1;179(1):26-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89