Sequence Detail

ID/Version

Q62217 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=Semaphorin-5A;AltName: Full=Semaphorin-F; Short=Sema F;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1077 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	50	120	3	13

Sequence references in MGI

J:34073 Adams RH, et al., A novel class of murine semaphorins with homology to thrombospondin is differentially expressed during early embryogenesis. Mech Dev. 1996 Jun;57(1):33-45
J:97663 Fiore R, et al., Inactivation of the Sema5a gene results in embryonic lethality and defective remodeling of the cranial vascular system. Mol Cell Biol. 2005 Mar;25(6):2310-9
J:174679 Matsuoka RL, et al., Class 5 transmembrane semaphorins control selective Mammalian retinal lamination and function. Neuron. 2011 Aug 11;71(3):460-73
J:203404 Sadanandam A, et al., Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis. Microvasc Res. 2010 Jan;79(1):1-9