Sequence Detail

ID/Version

Q62225 Q3TC70 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Cytokine-inducible SH2-containing protein; Short=CIS;AltName: Full=CIS-1;AltName: Full=Suppressor of cytokine signaling; Short=SOCS;

Provider

SWISS-PROT

Sequence

Polypeptide 257 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cish	cytokine inducible SH2-containing protein	9	101	4	14

Sequence references in MGI

J:26494 Yoshimura A, et al., A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J. 1995 Jun 15;14(12):2816-26
J:44332 Matsumoto A, et al., CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood. 1997 May 1;89(9):3148-54
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563