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Sequence Detail
ID/Version
Q62384 (UniProt | EBI) Last sequence update: 1996-11-01
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Zinc finger protein ZPR1;AltName: Full=Zinc finger protein 259;
Provider SWISS-PROT
Sequence
Polypeptide 459 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Zpr1 ZPR1 zinc finger 66 101 3 3
Sequence references in MGI J:50322 Galcheva-Gargova Z, et al., The cytoplasmic zinc finger protein ZPR1 accumulates in the nucleolus of proliferating cells. Mol Biol Cell. 1998 Oct;9(10):2963-71
J:50499 Galcheva-Gargova Z, et al., Binding of zinc finger protein ZPR1 to the epidermal growth factor receptor. Science. 1996 Jun 21;272(5269):1797-802
J:97582 Gangwani L, et al., ZPR1 is essential for survival and is required for localization of the survival motor neurons (SMN) protein to Cajal bodies. Mol Cell Biol. 2005 Apr;25(7):2744-56
J:109700 Doran B, et al., Deficiency of the zinc finger protein ZPR1 causes neurodegeneration. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7471-5
J:184463 Ahmad S, et al., The zinc finger protein ZPR1 is a potential modifier of spinal muscular atrophy. Hum Mol Genet. 2012 Jun 15;21(12):2745-58
J:206924 Gangwani L, et al., Interaction of ZPR1 with translation elongation factor-1alpha in proliferating cells. J Cell Biol. 1998 Dec 14;143(6):1471-84
J:248227 Mishra AK, et al., Structural insights into the interaction of the evolutionarily conserved ZPR1 domain tandem with eukaryotic EF1A, receptors, and SMN complexes. Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):13930-5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory