Sequence Detail

ID/Version

Q62414 Q925V5 Q61952 (UniProt | EBI)

Last sequence update: 2003-10-10
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Neurogenic differentiation factor 2; Short=NeuroD2;AltName: Full=NeuroD-related factor; Short=NDRF;

Provider

SWISS-PROT

Sequence

Polypeptide 383 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Neurod2	neurogenic differentiation 2	35	116	3	9

Sequence references in MGI

J:32452 Yasunami M, et al., Molecular cloning and characterization of a cDNA encoding a novel basic helix-loop-helix protein structurally related to Neuro-D/BHF1. Biochem Biophys Res Commun. 1996 Mar 27;220(3):754-8
J:35346 McCormick MB, et al., NeuroD2 and neuroD3: distinct expression patterns and transcriptional activation potentials within the neuroD gene family. Mol Cell Biol. 1996 Oct;16(10):5792-800
J:62191 Oda H, et al., Structure of the mouse NDRF gene and its regulation during neuronal differentiation of P19 cells. Brain Res Mol Brain Res. 2000 Apr 14;77(1):37-46
J:69606 Olson JM, et al., NeuroD2 is necessary for development and survival of central nervous system neurons. Dev Biol. 2001 Jun 1;234(1):174-87
J:87366 Lin CH, et al., Regulation of neuroD2 expression in mouse brain. Dev Biol. 2004 Jan 1;265(1):234-45
J:102471 Lin CH, et al., The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14877-82
J:107599 Ince-Dunn G, et al., Regulation of thalamocortical patterning and synaptic maturation by NeuroD2. Neuron. 2006 Mar 2;49(5):683-95
J:134786 Ravanpay AC, et al., E protein dosage influences brain development more than family member identity. J Neurosci Res. 2008 May 15;86(7):1472-81
J:164132 Ravanpay AC, et al., Transcriptional inhibition of REST by NeuroD2 during neuronal differentiation. Mol Cell Neurosci. 2010 Jun;44(2):178-89
J:172912 Farah MH, et al., Generation of neurons by transient expression of neural bHLH proteins in mammalian cells. Development. 2000 Feb;127(4):693-702
J:172950 Yang Y, et al., A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation. Science. 2009 Oct 23;326(5952):575-8
J:172992 Noda T, et al., Transduction of NeuroD2 protein induced neural cell differentiation. J Biotechnol. 2006 Nov 1;126(2):230-6