Sequence Detail

ID/Version

Q62431 Q80YP8 Q3U338 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2024-05-29

Sequence description from provider

RecName: Full=AT-rich interactive domain-containing protein 3A; Short=ARID domain-containing protein 3A;AltName: Full=B-cell regulator of IgH transcription; Short=Bright;AltName: Full=Dead ringer-like protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 601 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arid3a	AT-rich interaction domain 3A	18	107	3	7

Sequence references in MGI

J:51742 Herrscher RF, et al., The immunoglobulin heavy-chain matrix-associating regions are bound by Bright: a B cell-specific trans-activator that describes a new DNA-binding protein family. Genes Dev. 1995 Dec 15;9(24):3067-82
J:95172 Nixon JC, et al., Mutations in the DNA-binding domain of the transcription factor Bright act as dominant negative proteins and interfere with immunoglobulin transactivation. J Biol Chem. 2004 Dec 10;279(50):52465-72
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106913 Kim D, et al., A regulated nucleocytoplasmic shuttle contributes to Bright's function as a transcriptional activator of immunoglobulin genes. Mol Cell Biol. 2006 Mar;26(6):2187-201
J:118397 Webb CF, et al., The transcription factor Bright associates with Bruton's tyrosine kinase, the defective protein in immunodeficiency disease. J Immunol. 2000 Dec 15;165(12):6956-65
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:144102 Shankar M, et al., Anti-nuclear antibody production and autoimmunity in transgenic mice that overexpress the transcription factor Bright. J Immunol. 2007 Mar 1;178(5):2996-3006
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89