Sequence Detail

ID/Version

Q64096 E9PV70 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Guanine nucleotide exchange factor DBS;AltName: Full=DBL's big sister;AltName: Full=MCF2-transforming sequence-like protein;

Provider

SWISS-PROT

Sequence

Polypeptide 1149 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mcf2l	mcf.2 transforming sequence-like	22	104	4	18

Sequence references in MGI

J:23628 Whitehead I, et al., Retroviral transduction and oncogenic selection of a cDNA encoding Dbs, a homolog of the Dbl guanine nucleotide exchange factor. Oncogene. 1995 Feb 16;10(4):713-21
J:114759 Rossman KL, et al., A crystallographic view of interactions between Dbs and Cdc42: PH domain-assisted guanine nucleotide exchange. EMBO J. 2002 Mar 15;21(6):1315-26
J:118143 Kostenko EV, et al., Ccpg1, a novel scaffold protein that regulates the activity of the Rho guanine nucleotide exchange factor Dbs. Mol Cell Biol. 2006 Dec;26(23):8964-75
J:175102 Snyder JT, et al., Structural basis for the selective activation of Rho GTPases by Dbl exchange factors. Nat Struct Biol. 2002 Jun;9(6):468-75
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89