Sequence Detail

ID/Version

Q64249 Q687Z3 A2AQL8 A2AQM1 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Nuclear receptor subfamily 6 group A member 1;AltName: Full=Germ cell nuclear factor {ECO:0000303|PubMed:27984042}; Short=GCNF {ECO:0000303|PubMed:27984042}; Short=mGCNF;AltName: Full=Retinoid receptor-related testis-specific

Provider

SWISS-PROT

Sequence

Polypeptide 495 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nr6a1	nuclear receptor subfamily 6, group A, member 1	26	135	4	91

Sequence references in MGI

J:21389 Chen F, et al., Cloning of a novel orphan receptor (GCNF) expressed during germ cell development. Mol Endocrinol. 1994 Oct;8(10):1434-44
J:22662 Hirose T, et al., RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis. Gene. 1995 Jan 23;152(2):247-51
J:23077 Seol W, et al., Isolation of proteins that interact specifically with the retinoid X receptor: two novel orphan receptors. Mol Endocrinol. 1995 Jan;9(1):72-85
J:71786 Fuhrmann G, et al., Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev Cell. 2001 Sep;1(3):377-87
J:82985 Yang G, et al., Analysis of germ cell nuclear factor transcripts and protein expression during spermatogenesis. Biol Reprod. 2003 May;68(5):1620-30
J:116260 Yan Z, et al., RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor. J Biol Chem. 2002 Aug 30;277(35):32379-88
J:122688 Joos TO, et al., xGCNF, a nuclear orphan receptor is expressed during neurulation in Xenopus laevis. Mech Dev. 1996 Nov;60(1):45-57
J:359790 Weikum ER, et al., A Structural Investigation into Oct4 Regulation by Orphan Nuclear Receptors, Germ Cell Nuclear Factor (GCNF), and Liver Receptor Homolog-1 (LRH-1). J Mol Biol. 2016 Dec 4;428(24 Pt B):4981-4992