Sequence Detail

ID/Version

Q64387 Q61105 Q61938 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Prepronociceptin;AltName: Full=N23K/N27K;Contains: RecName: Full=Nocistatin;Contains: RecName: Full=Nociceptin; AltName: Full=Orphanin FQ; AltName: Full=PPNOC;Contains: RecName: Full=Orphanin FQ2;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 187 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pnoc	prepronociceptin	19	104	4	10

Sequence references in MGI

J:30116 Saito Y, et al., N23K, a gene transiently up-regulated during neural differentiation, encodes a precursor protein for a newly identified neuropeptide nociceptin. Biochem Biophys Res Commun. 1995 Dec 14;217(2):539-45
J:31865 Houtani T, et al., Structure and regional distribution of nociceptin/orphanin FQ precursor. Biochem Biophys Res Commun. 1996 Feb 27;219(3):714-9
J:32541 Pan YX, et al., Cloning and expression of a cDNA encoding a mouse brain orphanin FQ/nociceptin precursor. Biochem J. 1996 Apr 1;315(Pt 1):11-3
J:33720 Saito Y, et al., Molecular cloning and characterization of a novel form of neuropeptide gene as a developmentally regulated molecule. J Biol Chem. 1996 Jun 28;271(26):15615-22
J:34825 Mollereau C, et al., Structure, tissue distribution, and chromosomal localization of the prepronociceptin gene. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8666-70
J:49919 Rossi GC, et al., Analgesic activity of orphanin FQ2, murine prepro-orphanin FQ141-157 in mice. Neuroreport. 1998 Apr 20;9(6):1165-8