Sequence Detail

ID/Version

Q6A037 Q3UY69 Q3UH87 Q3TCI4 (UniProt | EBI)

Last sequence update: 2007-09-11
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=NEDD4-binding protein 1 {ECO:0000303|PubMed:11717310}; Short=N4BP1 {ECO:0000303|PubMed:11717310}; EC=3.1.-.- {ECO:0000250|UniProtKB:O75113};

Provider

SWISS-PROT

Sequence

Polypeptide 893 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	N4bp1	NEDD4 binding protein 1	25	96	3	35

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143823 Oberst A, et al., The Nedd4-binding partner 1 (N4BP1) protein is an inhibitor of the E3 ligase Itch. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11280-5
J:159635 Sharma P, et al., N4BP1 is a newly identified nucleolar protein that undergoes SUMO-regulated polyubiquitylation and proteasomal turnover at promyelocytic leukemia nuclear bodies. J Cell Sci. 2010 Apr 15;123(Pt 8):1227-34
J:164713 Murillas R, et al., Identification of developmentally expressed proteins that functionally interact with Nedd4 ubiquitin ligase. J Biol Chem. 2002 Jan 25;277(4):2897-907
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:297419 Gitlin AD, et al., Integration of innate immune signalling by caspase-8 cleavage of N4BP1. Nature. 2020 Nov;587(7833):275-280