Sequence Detail

ID/Version

Q6A4J8 Q8BW01 Q496Y5 Q3UX92 (UniProt | EBI)

Last sequence update: 2004-09-13
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Ubiquitin carboxyl-terminal hydrolase 7; EC=3.4.19.12 {ECO:0000269|PubMed:14719112, ECO:0000269|PubMed:21268065};AltName: Full=Deubiquitinating enzyme 7;AltName: Full=Herpesvirus-associated ubiquitin-specific protease; Short=

Provider

SWISS-PROT

Sequence

Polypeptide 1103 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Usp7	ubiquitin specific peptidase 7	60	101	3	296

Sequence references in MGI

J:91346 Lim SK, et al., Identification and characterization of murine mHAUSP encoding a deubiquitinating enzyme that regulates the status of p53 ubiquitination. Int J Oncol. 2004 Feb;24(2):357-64
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:168184 Kon N, et al., Inactivation of HAUSP in vivo modulates p53 function. Oncogene. 2010 Mar 4;29(9):1270-9
J:188893 Qin W, et al., Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1. J Cell Biochem. 2011 Feb;112(2):439-44
J:238487 Liefke R, et al., EPOP Interacts with Elongin BC and USP7 to Modulate the Chromatin Landscape. Mol Cell. 2016 Nov 17;64(4):659-672
J:283196 Hirano A, et al., USP7 and TDP-43: Pleiotropic Regulation of Cryptochrome Protein Stability Paces the Oscillation of the Mammalian Circadian Clock. PLoS One. 2016;11(4):e0154263
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89