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Sequence Detail
ID/Version
Q6NVE9 Q3TS53 Q8BVC7 (UniProt | EBI) Last sequence update: 2004-07-05
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=Protein phosphatase PTC7 homolog; EC=3.1.3.16 {ECO:0000250|UniProtKB:Q8NI37};AltName: Full=T-cell activation protein phosphatase 2C; Short=TA-PP2C;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 310 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Pptc7 PTC7 protein phosphatase homolog 24 97 4 43
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:277086 Niemi NM, et al., Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis. Nat Commun. 2019 Jul 19;10(1):3197
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:344670 Niemi NM, et al., PPTC7 maintains mitochondrial protein content by suppressing receptor-mediated mitophagy. Nat Commun. 2023 Oct 13;14(1):6431

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory