Sequence Detail

ID/Version

Q6PDY2 Q3U2E1 (UniProt | EBI)

Last sequence update: 2006-02-21
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=2-aminoethanethiol dioxygenase; EC=1.13.11.19 {ECO:0000269|PubMed:17581819, ECO:0000269|PubMed:32601061};AltName: Full=Cysteamine dioxygenase;

Provider

SWISS-PROT

Sequence

Polypeptide 256 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ado	2-aminoethanethiol dioxygenase	9	98	3	7

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:124703 Dominy JE Jr, et al., Discovery and characterization of a second Mammalian thiol dioxygenase, cysteamine dioxygenase. J Biol Chem. 2007 Aug 31;282(35):25189-98
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:322370 Wang Y, et al., Characterization of the nonheme iron center of cysteamine dioxygenase and its interaction with substrates. J Biol Chem. 2020 Aug 14;295(33):11789-11802
J:322690 Fernandez RL, et al., The Crystal Structure of Cysteamine Dioxygenase Reveals the Origin of the Large Substrate Scope of This Vital Mammalian Enzyme. Biochemistry. 2021 Dec 7;60(48):3728-3737