Sequence Detail

ID/Version

Q6ZPR4 Q8C3E7 B2RUK3 C0KTP6 (UniProt | EBI)

Last sequence update: 2005-08-30
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Potassium channel subfamily T member 1;

Provider

SWISS-PROT

Sequence

Polypeptide 1224 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kcnt1	potassium channel, subfamily T, member 1	18	97	4	17

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161627 Brown MR, et al., Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack. Nat Neurosci. 2010 Jul;13(7):819-21
J:218978 Lu R, et al., Slack channels expressed in sensory neurons control neuropathic pain in mice. J Neurosci. 2015 Jan 21;35(3):1125-35
J:228059 Martinez-Espinosa PL, et al., Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neurons. Elife. 2015;4:e10013
J:287751 Quraishi IH, et al., Impaired motor skill learning and altered seizure susceptibility in mice with loss or gain of function of the Kcnt1 gene encoding Slack (KNa1.1) Na(+)-activated K(+) channels. Sci Rep. 2020 Feb 21;10(1):3213
J:347312 Matt L, et al., The Na(+)-activated K(+) channel Slack contributes to synaptic development and plasticity. Cell Mol Life Sci. 2021 Dec;78(23):7569-7587
J:355666 Rizzi S, et al., Identification of potential novel interaction partners of the sodium-activated potassium channels Slick and Slack in mouse brain. Biochem Biophys Rep. 2015 Dec;4:291-298