Sequence Detail

ID/Version

Q7TME0 B2RQ15 Q8BV73 Q8BXK2 Q8R3R6 Q6ZQA8 (UniProt | EBI)

Last sequence update: 2008-02-05
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Phospholipid phosphatase-related protein type 4 {ECO:0000250|UniProtKB:Q7Z2D5};AltName: Full=Brain-specific phosphatidic acid phosphatase-like protein 1 {ECO:0000250|UniProtKB:Q7Z2D5};AltName: Full=Inactive 2-lysophosphatidate phosphatase PL

Provider

SWISS-PROT

Sequence

Polypeptide 766 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Plppr4	phospholipid phosphatase related 4	32	100	3	5

Sequence references in MGI

J:85572 Brauer AU, et al., A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. Nat Neurosci. 2003 Jun;6(6):572-8
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:157318 Trimbuch T, et al., Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling. Cell. 2009 Sep 18;138(6):1222-35
J:229600 Vogt J, et al., Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. EMBO Mol Med. 2015;8(1):25-38
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:339777 Knierim E, et al., Mutations in plasticity-related-gene-1 (PRG-1) protein contribute to hippocampal seizure susceptibility and modify epileptic phenotype. Cereb Cortex. 2023 Jun 8;33(12):7454-7467