Sequence Detail

ID/Version

Q7TMS5 Q9Z1T0 Q9R004 (UniProt | EBI)

Last sequence update: 2003-10-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Broad substrate specificity ATP-binding cassette transporter ABCG2 {ECO:0000305}; EC=7.6.2.2 {ECO:0000269|PubMed:10485464, ECO:0000269|PubMed:12477054};AltName: Full=ATP-binding cassette sub-family G member 2;AltName: Full=Breast can

Provider

SWISS-PROT

Sequence

Polypeptide 657 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Abcg2	ATP binding cassette subfamily G member 2 (Junior blood group)	55	114	4	61

Sequence references in MGI

J:56609 Allikmets R, et al., A human placenta-specific ATP-binding cassette gene (ABCP) on chromosome 4q22 that is involved in multidrug resistance. Cancer Res. 1998 Dec 1;58(23):5337-9
J:57248 Allen JD, et al., The mouse Bcrp1/Mxr/Abcp gene: amplification and overexpression in cell lines selected for resistance to topotecan, mitoxantrone, or doxorubicin. Cancer Res. 1999 Sep 1;59(17):4237-41
J:80519 Jonker JW, et al., The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15649-54
J:118277 van Herwaarden AE, et al., Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk. Mol Cell Biol. 2007 Feb;27(4):1247-53
J:269673 Takada T, et al., Identification of ABCG2 as an Exporter of Uremic Toxin Indoxyl Sulfate in Mice and as a Crucial Factor Influencing CKD Progression. Sci Rep. 2018 Jul 24;8(1):11147
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89