Sequence Detail

ID/Version

Q7TN75 Q9EQ11 (UniProt | EBI)

Last sequence update: 2008-03-18
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Retrotransposon-derived protein PEG10 {ECO:0000305}; Short=MmPEG10 {ECO:0000303|PubMed:34413232};AltName: Full=Embryonal carcinoma differentiation regulated protein {ECO:0000303|PubMed:11574691};AltName: Full=Mammalian retrotransposo

Provider

SWISS-PROT

Sequence

Polypeptide 958 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Peg10	paternally expressed 10	19	128	1	6

Sequence references in MGI

J:72112 Shigemoto K, et al., Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting. Nucleic Acids Res. 2001 Oct 1;29(19):4079-88
J:72470 Steplewski A, et al., MyEF-3, a developmentally controlled brain-derived nuclear protein which specifically interacts with myelin basic protein proximal regulatory sequences. Biochem Biophys Res Commun. 1998 Feb 4;243(1):295-301
J:74244 Volff J, et al., Ty3/Gypsy retrotransposon fossils in mammalian genomes: did they evolve into new cellular functions?. Mol Biol Evol. 2001 Feb;18(2):266-70
J:84436 Ono R, et al., Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6. Genome Res. 2003 Jul;13(7):1696-705
J:106134 Ono R, et al., Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality. Nat Genet. 2006 Jan;38(1):101-6
J:125249 Hishida T, et al., peg10, an imprinted gene, plays a crucial role in adipocyte differentiation. FEBS Lett. 2007 Sep 4;581(22):4272-8
J:129019 Clark MB, et al., Mammalian Gene PEG10 Expresses Two Reading Frames by High Efficiency 1 Frameshifting in Embryonic-associated Tissues. J Biol Chem. 2007 Dec 28;282(52):37359-69
J:273456 Abed M, et al., The Gag protein PEG10 binds to RNA and regulates trophoblast stem cell lineage specification. PLoS One. 2019;14(4):e0214110
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87
J:314915 Segel M, et al., Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. Science. 2021 Aug 20;373(6557):882-889