Sequence Detail

ID/Version

Q80SY3 Q8BTL3 Q3TDQ6 Q8BW16 Q5I0V5 (UniProt | EBI)

Last sequence update: 2007-05-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=V-type proton ATPase subunit d 2; Short=V-ATPase subunit d 2;AltName: Full=Osteoclast-specific vacuolar ATP synthase;AltName: Full=Vacuolar proton pump subunit d 2;

Provider

SWISS-PROT

Sequence

Polypeptide 350 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Atp6v0d2	ATPase, H+ transporting, lysosomal V0 subunit D2	16	105	2	7

Sequence references in MGI

J:81717 Sun-Wada GH, et al., Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits. Gene. 2003 Jan 2;302(1-2):147-53
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117744 Lee SH, et al., v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formation. Nat Med. 2006 Dec;12(12):1403-9
J:327410 Nishi T, et al., Expression and function of the mouse V-ATPase d subunit isoforms. J Biol Chem. 2003 Nov 21;278(47):46396-402
J:347000 Choi C, et al., TM4SF19-mediated control of lysosomal activity in macrophages contributes to obesity-induced inflammation and metabolic dysfunction. Nat Commun. 2024 Mar 30;15(1):2779