Sequence Detail

ID/Version

Q80TM9 Q8C354 Q8C4X9 Q9WUM6 Q2YDV7 Q91XW6 Q8CBH0 Q99LG6 Q9EPW8 (UniProt | EBI)

Last sequence update: 2008-09-02
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Nischarin;AltName: Full=Imidazoline receptor 1; Short=I-1; Short=IR1;AltName: Full=Imidazoline receptor I-1-like protein;AltName: Full=Imidazoline-1 receptor; Short=I1R;

Provider

SWISS-PROT

Sequence

Polypeptide 1593 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nisch	nischarin	26	102	3	38

Sequence references in MGI

J:66342 Alahari SK, et al., Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. J Cell Biol. 2000 Dec 11;151(6):1141-54
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:93054 Alahari SK, et al., The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK. EMBO J. 2004 Jul 21;23(14):2777-88
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:101162 Reddig PJ, et al., Regulation of p21-activated kinase-independent Rac1 signal transduction by nischarin. J Biol Chem. 2005 Sep 2;280(35):30994-1002
J:137325 Ding Y, et al., Nischarin inhibits LIM kinase to regulate cofilin phosphorylation and cell invasion. Mol Cell Biol. 2008 Jun;28(11):3742-56
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89