ID/Version |
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Sequence description from provider |
RecName: Full=TIR domain-containing adapter molecule 1; Short=TICAM-1;AltName: Full=Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; Short=TIR domain-containing adapter protein inducing IFN-beta; | ||||||||||||||
Provider | SWISS-PROT | ||||||||||||||
Sequence |
Polypeptide
732
aa
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Source | |||||||||||||||
Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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Sequence references in MGI |
J:84679
Yamamoto M, et al., Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway. Science. 2003 Aug 1;301(5633):640-3
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563 J:100715 De Trez C, et al., TLR4 and Toll-IL-1 receptor domain-containing adapter-inducing IFN-beta, but not MyD88, regulate Escherichia coli-induced dendritic cell maturation and apoptosis in vivo. J Immunol. 2005 Jul 15;175(2):839-46 J:144594 Sanada T, et al., FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway. J Biol Chem. 2008 Dec 5;283(49):33858-64 J:173994 Zhang Z, et al., DDX1, DDX21, and DHX36 Helicases Form a Complex with the Adaptor Molecule TRIF to Sense dsRNA in Dendritic Cells. Immunity. 2011 Jun 24;34(6):866-78 J:224712 Hu YH, et al., WDFY1 mediates TLR3/4 signaling by recruiting TRIF. EMBO Rep. 2015 Apr;16(4):447-55 J:239773 Hu MM, et al., TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. J Immunol. 2015 Nov 01;195(9):4415-25 J:245346 Oganesyan G, et al., Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature. 2006 Jan 12;439(7073):208-11 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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