Sequence Detail

ID/Version

Q80WK2 Q14BU3 Q3V4C1 (UniProt | EBI)

Last sequence update: 2003-06-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Organic solute transporter subunit beta {ECO:0000303|PubMed:22535958}; Short=OST-beta {ECO:0000303|PubMed:17650074};AltName: Full=Solute carrier family 51 subunit beta;

Provider

SWISS-PROT

Sequence

Polypeptide 128 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc51b	solute carrier family 51, beta subunit	25	98	2	6

Sequence references in MGI

J:84527 Seward DJ, et al., Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta. J Biol Chem. 2003 Jul 25;278(30):27473-82
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106032 Dawson PA, et al., The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter. J Biol Chem. 2005 Feb 25;280(8):6960-8
J:111079 Frankenberg T, et al., Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids. Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G912-22
J:126544 Li N, et al., Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter. Biochem J. 2007 Nov 1;407(3):363-72
J:187538 Christian WV, et al., beta-Subunit of the Ostalpha-Ostbeta organic solute transporter is required not only for heterodimerization and trafficking but also for function. J Biol Chem. 2012 Jun 15;287(25):21233-43
J:250040 Ballatori N, et al., OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology. 2005 Dec;42(6):1270-9
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89