Sequence Detail

ID/Version

Q80Y84 Q5DTR9 Q8JZL8 Q8BLU1 (UniProt | EBI)

Last sequence update: 2003-06-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Lysine-specific demethylase 5B; EC=1.14.11.67 {ECO:0000269|PubMed:17310255};AltName: Full=Histone demethylase JARID1B;AltName: Full=Jumonji/ARID domain-containing protein 1B;AltName: Full=PLU-1;AltName: Full=[histone H3]-trimethyl-L-

Provider

SWISS-PROT

Sequence

Polypeptide 1544 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kdm5b	lysine demethylase 5B	41	115	4	213

Sequence references in MGI

J:82207 Madsen B, et al., Characterisation and developmental expression of mouse Plu-1, a homologue of a human nuclear protein (PLU-1) which is specifically up-regulated in breast cancer. Mech Dev. 2002 Dec;119 Suppl 1:S239-46
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:122689 Iwase S, et al., The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases. Cell. 2007 Mar 23;128(6):1077-88
J:176119 DiTacchio L, et al., Histone lysine demethylase JARID1a activates CLOCK-BMAL1 and influences the circadian clock. Science. 2011 Sep 30;333(6051):1881-5
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:319824 Martin HC, et al., Quantifying the contribution of recessive coding variation to developmental disorders. Science. 2018 Dec 7;362(6419):1161-1164