Sequence Detail

ID/Version

Q80Z19 Q8K0Q1 Q9Z2U5 A0A087WSG8 Q9CVG8 Q80Z17 Q0P637 (UniProt | EBI)

Last sequence update: 2023-02-22
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Mucin-2 {ECO:0000303|PubMed:9886986}; Short=MUC-2 {ECO:0000303|PubMed:9886986};AltName: Full=Colonic mucin {ECO:0000303|PubMed:9886986}; Short=MCM {ECO:0000303|PubMed:9886986};AltName: Full=Secreted gel-forming mucin {ECO:000

Provider

SWISS-PROT

Sequence

Polypeptide 4576 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Muc2	mucin 2	28	104	2	17

Sequence references in MGI

J:52364 van Klinken BJ, et al., Gastrointestinal expression and partial cDNA cloning of murine Muc2. Am J Physiol. 1999 Jan;276(1 Pt 1):G115-24
J:75047 Velcich A, et al., Colorectal cancer in mice genetically deficient in the mucin Muc2. Science. 2002 Mar 1;295(5560):1726-9
J:88341 Escande F, et al., The mouse secreted gel-forming mucin gene cluster. Biochim Biophys Acta. 2004 Feb 20;1676(3):240-50
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:142847 Johansson ME, et al., The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15064-9
J:150756 Johansson ME, et al., Proteomic analyses of the two mucus layers of the colon barrier reveal that their main component, the muc2 mucin, is strongly bound to the fcgbp protein. J Proteome Res. 2009 Jul;8(7):3549-57
J:297095 Bergstrom K, et al., Proximal colon-derived O-glycosylated mucus encapsulates and modulates the microbiota. Science. 2020 Oct 23;370(6515):467-472