Sequence Detail

ID/Version

Q80ZJ1 Q7TSK4 Q3USK1 Q810A2 Q9D3D5 (UniProt | EBI)

Last sequence update: 2004-12-21
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Ras-related protein Rap-2a; EC=3.6.5.2 {ECO:0000250|UniProtKB:P10114};Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 183 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rap2a	RAS related protein 2a	55	96	3	6

Sequence references in MGI

J:60992 Janoueix-Lerosey I, et al., Identification of a specific effector of the small GTP-binding protein Rap2. Eur J Biochem. 1998 Mar 1;252(2):290-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:138992 Ryu J, et al., Constitutively active Rap2 transgenic mice display fewer dendritic spines, reduced extracellular signal-regulated kinase signaling, enhanced long-term depression, and impaired spatial learning and fear extinction. J Neurosci. 2008 Aug 13;28(33):8178-88
J:142909 Uechi Y, et al., Rap2 function requires palmitoylation and recycling endosome localization. Biochem Biophys Res Commun. 2009 Jan 23;378(4):732-7
J:164745 Kawabe H, et al., Regulation of Rap2A by the ubiquitin ligase Nedd4-1 controls neurite development. Neuron. 2010 Feb 11;65(3):358-72
J:172908 Traver S, et al., RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Biochem J. 2000 Aug 15;350 Pt 1:19-29
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89