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Sequence Detail
ID/Version
Q8BG07 Q8BR69 Q6PDR0 Q3TD59 Q3UA19 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2024-07-24
Sequence
description
from provider
RecName: Full=5'-3' exonuclease PLD4 {ECO:0000305}; EC=3.1.16.1 {ECO:0000269|PubMed:30111894};AltName: Full=Choline phosphatase 4;AltName: Full=Phosphatidylcholine-hydrolyzing phospholipase D4;AltName: Full=Phospholipase D4; Short=PLD 4;
Provider SWISS-PROT
Sequence
Polypeptide 503 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Pld4 phospholipase D family member 4 22 104 2 8
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166815 Yoshikawa F, et al., Phospholipase d family member 4, a transmembrane glycoprotein with no phospholipase D activity, expression in spleen and early postnatal microglia. PLoS One. 2010;5(11):e13932
J:180963 Otani Y, et al., PLD$ is involved in phagocytosis of microglia: expression and localization changes of PLD4 are correlated with activation state of microglia. PLoS One. 2011;6(11):e27544
J:281205 Gavin AL, et al., PLD3 and PLD4 are single-stranded acid exonucleases that regulate endosomal nucleic-acid sensing. Nat Immunol. 2018 Sep;19(9):942-953
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory