Sequence Detail

ID/Version

Q8BGT0 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=Osteopetrosis-associated transmembrane protein 1;AltName: Full=Chloride channel 7 beta subunit;AltName: Full=Grey-lethal protein;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 338 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ostm1	osteopetrosis associated transmembrane protein 1	11	99	3	9

Sequence references in MGI

J:82658 Chalhoub N, et al., Grey-lethal mutation induces severe malignant autosomal recessive osteopetrosis in mouse and human. Nat Med. 2003 Apr;9(4):399-406
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106978 Lange PF, et al., ClC-7 requires Ostm1 as a beta-subunit to support bone resorption and lysosomal function. Nature. 2006 Mar 9;440(7081):220-3
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89