Sequence Detail

ID/Version

Q8BHH1 Q8JZU1 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Aquaporin-11 {ECO:0000305|Ref.1}; Short=AQP-11 {ECO:0000305|Ref.1};

Provider

SWISS-PROT

Sequence

Polypeptide 271 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aqp11	aquaporin 11	44	110	3	12

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100522 Morishita Y, et al., Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Mol Cell Biol. 2005 Sep;25(17):7770-9
J:140244 Okada S, et al., Aquaporin-11 knockout mice and polycystic kidney disease animals share a common mechanism of cyst formation. FASEB J. 2008 Oct;22(10):3672-84
J:169660 Tchekneva EE, et al., Single amino acid substitution in aquaporin 11 causes renal failure. J Am Soc Nephrol. 2008 Oct;19(10):1955-64
J:194939 Rojek A, et al., Liver-specific Aquaporin 11 knockout mice show rapid vacuolization of the rough endoplasmic reticulum in periportal hepatocytes after amino acid feeding. Am J Physiol Gastrointest Liver Physiol. 2013 Mar 1;304(5):G501-15
J:197257 Atochina-Vasserman EN, et al., Aquaporin 11 insufficiency modulates kidney susceptibility to oxidative stress. Am J Physiol Renal Physiol. 2013 May;304(10):F1295-307
J:226888 Inoue Y, et al., Aberrant glycosylation and localization of polycystin-1 cause polycystic kidney in an AQP11 knockout model. J Am Soc Nephrol. 2014 Dec;25(12):2789-99
J:279938 Ikeda M, et al., The NPC motif of aquaporin-11, unlike the NPA motif of known aquaporins, is essential for full expression of molecular function. J Biol Chem. 2011 Feb 4;286(5):3342-50
J:279944 Yakata K, et al., Water permeability and characterization of aquaporin-11. J Struct Biol. 2011 May;174(2):315-20
J:280414 Rutzler M, et al., Temporal deletion of Aqp11 in mice is linked to the severity of cyst-like disease. Am J Physiol Renal Physiol. 2017 Feb 1;312(2):F343-F351
J:281183 Hoshino Y, et al., Involvement of the NADPH oxidase 2 pathway in renal oxidative stress in Aqp11 (-/-) mice. Biochem Biophys Rep. 2019 Mar;17:169-176
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89