Sequence Detail

ID/Version

Q8BIA4 Q8BI75 Q8CID8 Q8BI62 Q8BI76 Q921Z1 (UniProt | EBI)

Last sequence update: 2003-10-03
Last annotation update: 2024-11-27

Sequence description from provider

RecName: Full=F-box/WD repeat-containing protein 8;AltName: Full=F-box and WD-40 domain-containing protein 8;

Provider

SWISS-PROT

Sequence

Polypeptide 598 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fbxw8	F-box and WD-40 domain protein 8	43	99	3	19

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111403 Tsunematsu R, et al., Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development. Mol Cell Biol. 2006 Aug;26(16):6157-69
J:130238 Tsutsumi T, et al., Disruption of the Fbxw8 gene results in pre- and postnatal growth retardation in mice. Mol Cell Biol. 2008 Jan;28(2):743-51
J:259122 Bae KB, et al., Serine 347 Phosphorylation by JNKs Negatively Regulates OCT4 Protein Stability in Mouse Embryonic Stem Cells. Stem Cell Reports. 2017 Dec 12;9(6):2050-2064
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89