Sequence Detail

ID/Version

Q8BLF1 Q69ZL0 Q8BZK3 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Neutral cholesterol ester hydrolase 1; Short=NCEH; EC=3.1.1.- {ECO:0000269|PubMed:18782767, ECO:0000269|PubMed:20625037};AltName: Full=Acetylalkylglycerol acetylhydrolase {ECO:0000305}; Short=2-acetyl MAGE hydrolase {

Provider

SWISS-PROT

Sequence

Polypeptide 408 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nceh1	neutral cholesterol ester hydrolase 1	11	97	4	16

Sequence references in MGI

J:92575 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2004 Jun 30;11(3):205-18
J:98213 Nomura DK, et al., A brain detoxifying enzyme for organophosphorus nerve poisons. Proc Natl Acad Sci U S A. 2005 Apr 26;102(17):6195-200
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143389 Okazaki H, et al., Identification of neutral cholesterol ester hydrolase, a key enzyme removing cholesterol from macrophages. J Biol Chem. 2008 Nov 28;283(48):33357-64
J:165450 Buchebner M, et al., Cholesteryl ester hydrolase activity is abolished in HSL-/- macrophages but unchanged in macrophages lacking KIAA1363. J Lipid Res. 2010 Oct;51(10):2896-908
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89