Sequence Detail

ID/Version

Q8BMF8 Q80ZC5 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Gliomedin;AltName: Full=Cancer-related gene liver 2 protein; Short=CRG-L2;Contains: RecName: Full=Gliomedin shedded ectodomain;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 549 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Gldn	gliomedin	16	98	3	6

Sequence references in MGI

J:86019 Graveel CR, et al., Identification and characterization of CRG-L2, a new marker for liver tumor development. Oncogene. 2003 Mar 20;22(11):1730-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:121159 Maertens B, et al., Cleavage and oligomerization of gliomedin, a transmembrane collagen required for node of ranvier formation. J Biol Chem. 2007 Apr;282(14):10647-59
J:166099 Feinberg K, et al., A glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of Ranvier. Neuron. 2010 Feb 25;65(4):490-502
J:203534 Kwon HS, et al., Myocilin mediates myelination in the peripheral nervous system through ErbB2/3 signaling. J Biol Chem. 2013 Sep 13;288(37):26357-71
J:208118 Amor V, et al., Long-Term Maintenance of Na+ Channels at Nodes of Ranvier Depends on Glial Contact Mediated by Gliomedin and NrCAM. J Neurosci. 2014 Apr 9;34(15):5089-98