Sequence Detail

ID/Version

Q8BRM6 Q8C4E8 Q4V9Z7 (UniProt | EBI)

Last sequence update: 2003-03-01
Last annotation update: 2024-07-24

Sequence description from provider

RecName: Full=Meiosis-specific protein MEI4 {ECO:0000305};

Provider

SWISS-PROT

Sequence

Polypeptide 389 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mei4	meiotic double-stranded break formation protein 4	15	97	3	5

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161203 Kumar R, et al., Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to mice. Genes Dev. 2010 Jun 15;24(12):1266-80
J:231710 Kumar R, et al., MEI4 - a central player in the regulation of meiotic DNA double-strand break formation in the mouse. J Cell Sci. 2015 May 1;128(9):1800-11
J:238496 Stanzione M, et al., Meiotic DNA break formation requires the unsynapsed chromosome axis-binding protein IHO1 (CCDC36) in mice. Nat Cell Biol. 2016 Nov;18(11):1208-1220
J:271216 Kumar R, et al., Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4. Life Sci Alliance. 2018 Dec;1(6):e201800259