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Sequence Detail
ID/Version
Q8BUW1 Q9CX88 A0A1Y7VJZ9 F6YU65 (UniProt | EBI) Last sequence update: 2003-03-01
Last annotation update: 2025-02-05
Sequence
description
from provider
RecName: Full=Potassium channel subfamily K member 10;AltName: Full=Outward rectifying potassium channel protein TREK-2;AltName: Full=TREK-2 K(+) channel subunit;
Provider SWISS-PROT
Sequence
Polypeptide 535 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Kcnk10 potassium channel, subfamily K, member 10 5 100 4 5
Sequence references in MGI J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:232118 Blin S, et al., Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties. Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):4200-5
J:270313 Royal P, et al., Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK. Neuron. 2019 Jan 16;101(2):232-245.e6
J:298729 Lengyel M, et al., TRESK and TREK-2 two-pore-domain potassium channel subunits form functional heterodimers in primary somatosensory neurons. J Biol Chem. 2020 Aug 28;295(35):12408-12425

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory